Recently，The college’s discharge plasma and its biomedical application team is inPlasma Processes and PolymersMagazine published withNumerical study on interactions of atmospheric plasmas and vegetable oils by reactive molecular dynamic simulations Research results on the topic，This article was selected as the cover article。The first author of this article is Tian Shuqi, a master’s student co-supervised by Professor Zhang Yuantao and Associate Professor Wang Xiaolong，Professor Zhang Yuantao is the corresponding author。
Picture1 Cover Page
The plasma generated by high-voltage discharge contains a large number of highly active particles，These active particles are both charged and neutral，This article uses reactive molecular dynamics simulation methods to study reactive oxygen particles generated in atmospheric pressure plasma(ROS), like ground stateOatom,OHFree radical sumO3molecules, as well as fatty acids, the main active ingredients in vegetable oilsReaxFFReaction process under the action of force field，In-depth exploration at the atomic level of the breaking and forming of chemical bonds in fatty acid molecules oxidized by active particles。For example, the ground-state oxygen atoms provided in the plasma can cause the methyl group at the end of the original hydrocarbon chain to form an alkyl radical，At the same time accompanied by oneOHGeneration of free radicals(As shown in the picture2（a) and (b）). Subsequently, thisOHThe free radical attaches to the formed alkyl radical, in the figure2（c) to form an alcohol group。This reaction can be carried out further，Finally forms an aldehyde group(See picture2（d)）。Aldehydes observed on fatty acid molecules、Generation of oxygen-containing functional groups such as alcohols，This is consistent with what was observed in the experimentPAOThe results of changes in molecular structure are consistent。Based on calculated data，The article shows that under the influence of reactive oxygen speciesPAO9217_9222。This study reveals the breaking and formation of chemical bonds in liquids under the action of plasma active particles，And the synthesis of new active groups。Water treatment by discharge plasma、Solution、Liquid substances such as grease，Can effectively generate demand instantly、Instant use of plasma active particles transformed into many types、Active group with long storage period，Thus providing the possibility for the development of plasma medicine。
Picture2 Generation of alcohol and aldehyde groups
Associate Professor Zhao Tong’s article on plasma killing of the new coronavirus is also hereJournal of Physics D: Applied PhysicsPosted，This article profoundly reveals the specific mechanism of the interaction between discharge plasma and new coronavirus proteins from a microscopic perspective，Deepened the understanding of the mechanism of plasma killing the new coronavirus，Provides a theoretical basis for the large-scale application of discharge plasma rapid disinfection。
Picture3 Oxygen atoms and the new coronavirusfibrillar proteinProcess
Plasma medicine is a rapidly developing cross-research field，It is also the forefront of bioelectromagnetic research。Plasma medicine has developed very rapidly in the past ten years，Brings new ideas to the medical treatment of certain diseases、New methods and new technologies，It even brings new hope for the treatment of cancer。In recent years，Our hospital’s discharge plasma and its biomedical application team，Focus on the field of plasma medical research，With Shandong University School of Medicine、School of Pharmacy、Cooperation with Qilu Hospital and Shandong Academy of Agricultural Sciences and other units，A series of original achievements have been achieved in the intersection of medicine and engineering，Formed a unique research direction。
