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Recent，Discharge plasma and its biomedical application team, Associate Professor Zhao Tong Zhao Tong in the international journalPHYSICS of PlasmasMagazine published the title"Molecular Dynamics Simulations of the Permeration M88 Online Live Casinoand Distribution of Plasma Ros in Aquaporin-"research papers, and were selected asEditor's PickArticle (Editor's Picks Serve to Highlight Articles with ExcelLorentic Quality and Are REPRESENTIVE of The Work Taking Place in A Special Field）。
In recent years, atmospheric pressure low temperature plasma (CAP) Selective induced tumor cell apoptosis has become a research hotspot，But its specific mechanism is unclear。Water Channel protein (AQPS) It is considered to beCAPThe key to selectively treat the cancer mechanism。In this study，CAPActive oxygen particles generated (ROS) Through water channel protein-1（AQP1) Selective transgender transportation m88 sports bettingon cancer cell membrane，So as to provide micro evidence for plasma activated cancer cells。Based ongromos 53A6Power field, determined through classic molecular dynamic simulation, determinedROSThe membrane penetration process,ROSdistribution on cancer cell membranes andROSinAQP16013_6021ROSdistribution indicatesAQP1Existence leading to hydrophilicityROSThe distribution on the cell membrane is more deeper. At the same time, hydrophilicityROSThroughAQP1The freedom of exercise can be significantly lower than the freedom of exercise on normal lipid bipoles。Therefore，Oncocyte filmAQP1Excessive expression can improve hydrophilicityROSEfficiency of entering cancer cells。These results indicate，Oncocyte filmAQP1The existence can be increasedROSThe efficiency of cross -membrane transportation, and revealed at the atomic levelCAPMicro mechanism of selective divertal cancer cells，helps to deepen people's understanding of plasma auxiliary cancer treatment。
Associate Professor Zhao Tong is the author of the paper，Master Graduate Wang Zizhen as the first author，This research work has obtained the National Natural Science Foundation of China、Funding from the Shandong Natural Science Foundation。
Original link:https://doi.org/10.1063/5.0057240
